| TABLE 1: Classes of Drugs That May Cause Photosensitivity |
| Antiarrhythmics |
| Antibiotics (fluoroquinolones, tetracyclines) |
| Anticholinergics |
| Antidepressants |
| Antihistamines |
| Antipsychotic agents |
| Cardiac agents (angiotensin converting enzyme inhibitors, calcium channel blockers) |
| Central nervous system stimulants |
| Digitalis glycosides |
| Folic acid antagonists |
| Herbs, such as St. John’s wort (Hypericum perforatum) |
| Nonsteroidal anti-inflammatory drugs (NSAIDs) |
| Oral contraceptives |
| Phenothiazines (tranquilizers) |
| Psoralens (for psoriasis) |
| Retinoids (isotretinoin) |
| Thiazide diuretics |
| TABLE 2: Selected Classes of Drugs Implicated in the Development of Ocular Diseases |
| Drug class |
Potential ocular diseases implicated |
| Antiarrhythmic agents: |
Keratopathy, optic neuropathy |
| Antineoplastic agents: |
Keratitis, scleritis, color blindness, internal ophthalmoplegia, retinopathy, papilledema, maculopathy, dry eyes, cataract, glaucoma, optic neuritis, blepharitis |
| Antipsychotic agents: |
Cataracts, keratopathy |
| Bisphosphonates: |
Conjunctivitis, scleritis, uveitis |
| Corticosteroids: |
Cataracts, glaucoma |
| Dermatologic agents (isotretinoin): |
Keratopathy, dry eye, optic neuritis,
night blindness, blepharoconjunctivitis |
| HIV/AIDS-related agents: |
Night blindness, retinal detachment,
glaucoma, cataract, maculopathy,
retinopathy, optic neuritis,
conjunctivitis |
|